Cell Advanced Manufacturing & Production

CREATE Symposium | CREATE Tower | 1 CREATE Way | Singapore 138602

Symposium Scope

  1. CLINICAL NEEDS: Current obstacles to cells-as-product reaching clinical trials, translation, safety/regulation, commercialization; includes     personalized medicine with various sources of stem, progenitor, and engineered immune cells, as well as the microbiome.
  2. MANUFACTURING ROADMAPS AND INDUSTRY CHALLENGES: Process for identifying pre-competitive research and development, and workforce training opportunities, to advance industry. Technical needs in cell selection, expansion, quality/safety, packaging, and associated skilled workforces.
  3. TECHNOLOGY INNOVATION: New ideas, devices, and infrastructure for advanced manufacturing in Singapore and internationally, to reduce time and cost and improve quality for commercial production of new and emerging cell-based therapies.


08:00am    Registration & Breakfast

08:30am    Welcome: Dr. Khiang Wee Lim (CREATE and Singapore National Research Foundation, Executive Director)

​                                 Prof. Kong Peng Lam (A*STAR Bioprocessing Technology Institute, Executive Director)

                                 Prof. Daniel Hastings (SMART, Director and CEO)

                                 Prof. Krystyn Van Vliet (SMART BioSystems & Micromechanics and MIT, Lead PI)

9:00am    Clinical Needs: Singapore Challenges. 

                                 Dr. Tricia Huang (National Medical Research Council and Ministry of Health Singapore)

                                 Dr. William Hwang (Singapore General Hospital and Singapore Cord Blood Bank)

                                 Dr. Russell Gruen (LKC School of Medicine, Nanyang Technological University)

                                 Dr. Antonio Bertoletti (Duke-NUS)

10:15am    Tea Break and Networking

10:45am    Manufacturing Roadmaps and Industry Challenges: US and Singapore. 

                                 Prof. Krystyn Van Vliet (MIT, US Manufacturing Foresight Council)

                                 Dr. Donald Fink (US Food & Drug Administration)​​
                                   Dr. Samantha Maragh (US National Institute for Standards and Technology)
                                 Dr. Stacy Springs (MIT BioMAN)

​                                 Dr. Annie Koh (Singapore Management University)

12:30pm    Lunch with Industry Demonstrations & Researcher Posters

01:30pm    Technology Innovation: From bench to industry

                                 Prof. CT Lim (NUS Biomedical Engineering and Clearbridge Accelerator)

                                 Dr. Steve Oh (A*STAR Bioprocessing Technology Institute)

                                 Dr. Bruce Levine (Novartis-Penn Center for Advanced Cellular Therapeutics)

                                 Dr. Phan Toan Thang (Cell Research Corporation)​​

                                 Prof. Luke Lee (NUS Biomedical Institute for Global Health Research & Technology (BIGHEART))

02:45pm    Tea Break and Networking

03:00pm    Technology Innovation: From lab to clinic

                                  Dr. Zhiyong Poon (Singapore General Hospital) 

                                  Prof. Rajeev Ram (MIT)

                                  Prof. Antonio Bertoletti (Duke-NUS and LION TCR)

                                  Prof. Tim Lu (MIT)

                                  Dr. Samantha Maragh (US National Institute for Standards and Technology)

04:15pm    Stakeholder Panel Discussion: How do we realize this opportunity together?
                                 Moderated by Prof. Charlie Cooney, SMART Innovation Centre and Dr. Steve Oh, A*STAR BTI
05:00pm    Concluding remarks

06:00pm    Speaker Dinner (by invitation)

Organizing Committee                                              Key Industry Sponsor:

Singapore-MIT Alliance for Research & Technology (SMART) BioSystems & Micromechanics                                                  

A*STAR Bioprocessing Technology Institute

MIT BioMANufacturing Program